Scientific program
The
scientific program as described below has been organized by the
Scientific Committee. It is made of one keynote talk that will be
delivered by Dr Eric Green, scientific director of NHGRI, 11
scientific sessions covering all aspects of canine and feline
genomics from genome structure and evolution to Mendelian and complex
inherited diseases as well as phenotype-genotype relationship for
some important physiological traits.
Anne-Sophie Lequarré as leader of the LUPA project recently funded by the European
Community has been invited to provide the entire community with the
aim and topics of this project.
In
addition 2 poster sessions will allow a broader overview of on-going research in canine and feline genetics.
All
talks presented during the scientific sessions outlined below will be
selected by members of the scientific committee from the bulk of
abstracts submitted before February 15th.
Scientific
Committee members.
Danika
Bannasch, University of California, Davis.
Steve
O'Brien, National Cancer Institute, Frederick.
Francis
Galibert, Université de Rennes 1, France.
Urs
Giger, University of Pennsylvania, Philadelphia.
Steven
Hannah, Nestlé Purina Petcare Company, Saint Louis.
Kerstin
Lindblad-Toh, Broad Institute of Harvard, Cambridge.
Marilyn
Menotti-Raymond, National Cancer Institute, Frederick.
William
Murphy, Texas A&M University, College Station.
Elaine
Ostrander, National Human Genome Research Institute, Bethesda.
Timetable
Thursday
22nd
8.30 a.m.
Welcome
address: Francis Galibert
Keynote Green
Eric
Fulfilling
the Promise of a Sequenced Human Genome
9.30 a.m.
Chair: Elaine Ostrander:
Genomics Developments in Canine and Felines I
Hitte
Christophe
Targeted Identification
of New Genes and Gene Loss
in the
Domestic Dog Genome
Davis
Brian
A 900-KB Resolution
Radiation Hybrid and Integrated Fish Mapping Resource of Domestic Cat
Genome
Refines Evolutionary Breakpoints
Mullikin
James C.
Discovery of Three Million
SNPs Across 7 Breeds of Domestic Cat and One Wild Cat
10.45 a.m.
Coffee Break
11.05 a.m.
Chair:
Catherine André:
Genetics
of Canine and Feline Morphology I
Andersson Leif
Strong selection at the MITF locus
has shaped various spotting patterns in dogs
David A.
Victor
Four independent
mutations characterized in the FGF5 gene act in multiple allelic
combinations
to cause the long hair phenotype in the domestic cat
Kaelin
Christopher A
Segmental Duplication
Causes Brindled Coat Colour: Mechanisms and Implications
12.20 p.m.
lunch
1.20 p.m. Poster Session I
2.30 p.m.
Chair:Marilyn
Menotti-Raymond
Genetics
of Single Gene Traits I
Fyfe C.John
Molecular Investigation of Canine
Pontocerebellar Hypoplasia with Ventral Horn Cell Disease
Leegwater
A. Peter. A
Retracted DNA Repeat is
Associated with Pituitary Dwarfism in German Sheperd Dogs
Menotti-Raymond
M. Mutation Causative of
Retinal
Degeneration in the Abyssinian Cat (RDAC) Representative of a Newly
Emerging
Class of Genetic Disorder, A Ciliopathy
Wade .M.
Claire.
Mapping Degenerative
Myelopathy in Pembroke Welsh Corgis
4.10 p.m. Coffee break
4.30 a.m.
Chair:
Stephen J.
O'Brien
Genetics
of Infectious Diseases and Cancer
O’Brien J.
Stephen
Feline Genomics and Infectious
Diseases
Andersson
Goran
Identification of Canine
Endogenous Retroviruses in the Dog Genome Using Retrotector-
Evolutionary
Implications
Andre
Catherine
Analysis of the Genetic
Causes of Malignant Histiocytosis in the Bernese Mountain Dog
Thomas
Rachael. Development
of a FeLine
Genomic Microarray for Cytogenetic Profiling of Tumours
6.10 p.m. adjourn
7.00 p.m. Concert& Dinner
Friday 23rd
8.30 a.m.
Chair: Kerstin Lindblah-Toh
Genetics
of Complex Traits
Lindblad-
Toh K.
Complex Trait Mapping in
the Domestic Dog- Lessons Learnt
Karlsson
Elinor
Mapping Complex Traits in
Dogs Using Haplotype Association
Ostrander,
Elaine A. Dog
Genes Tell Surprising
Tales: Mapping Genes for Complex Traits
Distl
Ottmar
Unravelling the
Genetics of Canine Hip Dysplasia (CHD) in the German Shepherd Dogs
Using
Associated SNP Polymorphisms
10.10 a.m. Coffee break
10.30 a.m.
Chair: Murphy, William J.
Genomics
Developments in Canines and Felines II
Murphy,
William J.
Y Chromosome Gene Evolution
and Function in the Cat and Dog Genomes
Pecon-
Slattery, Jill
New Genomic and Sequence
Data from the Domestic Cat and its Relatives Provide Incentive for
Renewed
Focus on Y Chromosome Evolution
Neff Mark
Infinium CanineSNP20
BeadChip: Illumina's 22,000 SNP Array For Genome- Wide Association and
Phylogenetic Analysis in the Dog
Genetics of
Single Gene Traits II
Godiksen
Nyberg
Myosin Binding Protein C
(MyBPC3) Associated Feline Hypertonic Cardiomyopathy (HCM) is a
recessive
disease in young cats
12.10 p.m. Lunch
1.10 p.m. Poster session II & Coffee
2.40 p.m.
Chair:
Danika Bannasch
Genetics
of Single Gene Traits II (con’d)
Lohi
Hannes
Genetic analysis of
benign juvenile epilepsy in Lagotto Romagnolos
Haskins
Mark
Molecular Basis of Acute
Intermittent Porphyria in the Cat
Goldstein
E.Richard. Primary
Hyperoxaluria in Cats
is Caused by a Mutation in the Feline GRHPR Gene
Mickelson
R. James. A Dynamin 1 (DNM1)
Mutation is
Highly Associated with the Syndrome of Exercise- Induced Collapse in
Labrador
Retrievers
4.30 p.m. adjourn
5.00 p.m. Departure to Mont Saint Michel
9.00 p.m. Dinner
Saturday 24th
8.30 a.m.
Special Guest
Anne-Sophie
Lequarré
LUPA a
european initiativeat to unravel the molecular basis of common complex
human
disorders using the dog as a model system
8.55 a.m.
Chair:
Robert Wayne
Evolutionary
Dynamics
Anderson
M. Tovi
Evolutionary History and
Molecular Basis of Adaptive Melanism in Arctic Wolves: Reverse Gene
Transfer
Wayne
Robert
High Resolution SNP
Analysis of Dogs and Dog- like Carnivores
Webster T.
Matthew The
Legacy of Domestication:
Accumulation of Deleterious Mutations in the Dog Genome
10.10 a.m. Coffee Break
10.30 a.m.
Chair:
Gordon K Lark
Genetics
of Canine and Feline Morphology II
Lark
K. Gordon. Mapping
Dog
Stereotypes
BrandG.
Joseph
Taste Genetics and Food
Choices in Carnivores
Fondon John
Mouse Models of Dog Coding Repeat
Variations
Yokoyama
Jennifer Investigating
the Genetic
Basis of Noise Phobia in Herding Breed Dogs Via Genome Wide Survey
12.10 p.m. Lunch
1.30 p.m.
Hannes
Lohi
Population
Dynamics
Johnson
E.Warren . An
Assessment of Florida
Panther Fitness Correlates Derived From Long-term Pedigree and Life
History
Data
Chang
L.Melanie .
Intra-breed
Stratification Related to Divergent Selection Regimes in Purebreed Dogs
Affects
the Interpretation of Genetic Association Studies
Hedhammar
Ake.
Insurance Claim Data as Basis
for Molecular Genetic Studies in Dogs
2.50 p.m. Coffee break
3.10 p.m.
Chair:
Urs Giger
Genetics
of Single Gene Traits III
Mary Jerome.
Centronuclear Myopathy, Type-II
Deficiency Myopathy and Hereditary Myopathy of the Labrador Retriever
Result
from a Single Worldwide Mutation with a Founder Effect
Baranowska
Izabella Sensory Ataxic
Neuropathy in
Golden Retrievers is Associated With a Deletion in the Mitochondrial
tRNA- Tyr
gene
Kukekova
V. Anna . Canine
RD3 Mutation
Establishes Rod Cone Dysplasia Type 2 (RCD2) as the Canine Ortholog of
Human
and Murine RD3
Wiik Anne
Caroline A
mutation in a novel gene is
associated with recessive cone-rod dystrophy in a standard wire haired
dachshund
5.00 p.m.
Closure
remarks
Elaine
Ostrander & Steve O'Brien
5.20 End of Meeting
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